BIOCHEMICAL PROFILE:
Total
protein levels were estimated in the myelin membrane of the brain cells
obtained from all groups of rats. In Table.2, the results of the assay in group
II rats under stress showed increased levels of protein in myelin conforming
that considerable membrane damage has occurred due to lipid per oxidation in
these groups reflecting in the protein levels when compared to control. As
promotion of inflammatory destruction of protein caused by depression may get
to negatively influence cardiovascular health (Jesse Stewart 2009).
ENZYME
ASSAY:
TABLE-2
The total protein in
the myelin 0f control and experimental rats
PARTICULARS
|
GROUP
I
|
GROUP
II
|
||||
FB
|
MB
|
HB
|
FB
|
MB
|
HB
|
|
Myelin
|
61.36 ± 2.2
|
62.31
± 2.0
|
62.40 ± 2.1
|
52.53
± 1.8**a
|
45.71
± 2.5***b
|
55.41
± 2.2*c
|
PROTEIN
|
851.26
±20.0
|
862.32
± 14.0
|
866.55
± 14.3
|
801.26 ± 25.5**a
|
643.41
± 15.5***b
|
800.34
±
1 5.6*c
|
Values are expressed as mean ± SD (n=6)
Myelin – mg / 250mg
Protein – µg / mg of myelin
Statistical representation was expressed as p<0.05
*a FB of group I compared with Group II
*b MB of group I compared with Group II
*c HB of group I compared with Group II
Graph
2
Myelin
weight of fore, mid and hind brain of control and experimental Rat.
Values are expressed as mean ± SD (n=6)
Myelin – mg / 250mg
Statistical representation was expressed as p<0.05
*a FB of group I compared with Group II
*b MB of group I compared with Group II
*c HB of group I compared with Group II
The
total protein in myelin of fore, mid and hind brain of control and experimental
Rat.
Values are expressed as mean ± SD (n=6)
Protein – µg / mg of myelin
Statistical representation was expressed as p<0.05
*a FB of group I compared with Group II
*b MB of group I compared with Group II
*c HB of group I compared with Group II
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