ACKNOWLEDGEMENT





ACKNOWLEDGEMENT
This dissertation would not have been possible without the guidance and the help of several individuals who in one way or another contributed and extended their valuable assistance in the preparation and completion of this study.
First and foremost, my utmost gratitude to Dr. A. J. Vanisree, Assistant Professor, Department of Biochemistry, University of Madras, Guindy Campus, Chennai- 600 025 for giving me a unique opportunity to work under his guidance.
I profoundly thank Dr. S. Niranjali Devaraj, Professor and Head, Department of Biochemistry, University of Madras, Guindy Campus, Chennai, for her kind constant support, encouragement throughout of my study and for the generosity in utilizing all the facilities of the department.
I gratefully acknowledge my gratitude to Dr. T. Devaki., Professor ,Dr. V. Elangovan., Reader, Dr. S. Subramaniam., Senior lecturer,Dr. G. Sudhandhiran., Senior lecturer, Department of Biochemistry, University of Madras, Guindy Campus, Chennai, for their kind support throughout the period of study.
I wish to express my special and heartful thanks to research scholars  Mr. V. Muthukumar, Mr. R. Vishal, Ms. V. C. Nathiya, Ms. Anjana Sadanand, Ms.Anjali Janardhanan, Mr. S. Arun, Department of Biochemistry, University of Madras, Guindy Campus, Chennai, for their invaluable help and encouragement throughout the period of study.
I wish to express my sincere thanks to Ms. B. N. Thilagavathi, Mr.Venkateswarlu Raavi and my dear friends whose continuous encouragement and support was unremitting source of inspiration for this work.
I also extend my thanks to the Non-teaching staffs of the Department of Biochemistry, University of Madras, for their kind co-operation.
I have no words to express my gratitude to my beloved father A. Mani, my mother M. Thanamathi  and my dear brothers  M. Anand kumar and   M. Amareson for their love and continuous support, without whom my work would ’nt have been success.
I express my sincere thanks to dear and near ones for the help rendered by them directly and indirectly throughout the course of my work.
Last but not the least, above all of us, the omnipresent God, for answering my prayers for giving me the strength to plod on despite my constitution wanting to give up and throw in the towel, thank you so much Dear Lord.

MATHANI M
                                                                               
                                                                               
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