SUMMERY AND CONCLUSION:
Stress
is the single most vicious killer. Emotional turmoils play an important role in
accelerating from aging to stroke till leading to suicide. There is urge for
the treatment of depression to overcome more aggressive effects caused by
antidepressant drug like SSRIs (Selective serotonin reuptake inhibitor). These
drugs have recently been revealed that, on long term intake have serious risks
and are linked to suicide, violence, psychosis, abnormal bleeding and tumors.
This necessitated us to research for more effective intervention for cure with
limiting or much lesser side effects. The findings of our study summarized
below
The
myelin protein of stress bearing animal was found to be decreased compared with
normal.
The
activity of ATPase was found to be decreased in the stress group rats compared
to the control rats.
PBC
such as, Hexose, Hexose amine, Fucose and Sialic acid levels found to be
decreased in the stress induced rats when compared to normal.
SDS
– PAGE of myelin the band shows appreciable changes in the fore, mid, hind
brain region of stress induced rats when compared to the control group of rats.
From
the present study, it was concluded that light induced stress changes the level
of glycoprotein components of myelin protein in fore, mid and hind brain
experimental models of rat, which evidence from our Histopathological,
Biochemical and behavioral result in our studies.
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